How do you administer Abilify Depot?
How do you administer Abilify Depot?
Abilify Maintena is only intended for intramuscular use and should not be administered intravenously or subcutaneously. It should only be administered by a healthcare professional. The suspension should be injected slowly as a single injection (doses must not be divided) into the gluteal or deltoid muscle.
How do you administer Abilify Maintena?
ABILIFY MAINTENA is only to be administered by intramuscular injection by a healthcare professional. The recommended starting and maintenance dose of ABILIFY MAINTENA is 400 mg monthly (no sooner than 26 days after the previous injection).
How do you prepare an aripiprazole injection?
Hold the syringe upright and advance the plunger rod slowly to expel the air. Expel air until suspension fills needle base. If it’s not possible to advance the plunger rod to expel the air, check that the plunger rod is rotated to a complete stop (see Figure 7). Inject slowly into the deltoid or gluteal muscle.
How many mL is Abilify Maintena 300 mg?
Vial: Preparation and Administration Instructions
| 400-mg Vial | 300-mg Vial | |
|---|---|---|
| Dose | Sterile Water for Injection | Dose |
| 400 mg | 1.9 mL | 300 mg |
What are the doses of Abilify Maintena?
Recommended starting and maintenance dose of ABILIFY MAINTENA is 400 mg once monthly. *Oral aripiprazole (10 mg to 20 mg) or current oral antipsychotic.
Is aripiprazole 4 weekly or monthly?
Aripiprazole LAI should be administered once monthly (not 4 weekly) by the intramuscular route into the gluteal or deltoid muscle. It should not be administered intravenously or subcutaneously. The recommended dose is 400mg once per calendar month if there are no tolerability, metabolism or interaction issues.
Where do you inject Abilify?
Aripiprazole is given by injection into the buttock or upper arm muscle by a health care professional, usually once every month. Some doses may be given once every 6 weeks or once every 2 months. Do not rub/massage the injection site after your dose.
How quickly does aripiprazole depot work?
For the first 2 weeks of the initial depot injection, oral aripiprazole should be continued to allow adequate time for the intramuscular medication to reach adequate plasma concentrations, which we know can take approximately 6–12 days.
Where do you inject ABILIFY?
What is the difference between Abilify and Abilify Maintena?
They both contain the active ingredient aripiprazole, an atypical antipsychotic, and are approved for the treatment of schizophrenia and bipolar disorder. Abilify is approved for other uses, too. Abilify comes as an oral medication taken daily, while Abilify Maintena is a long-acting injection given every 4 weeks.
How long does Abilify injection stay in your system?
The half-life of Abilify Maintena is about 30 to 45 days, depending on your dose. A drug’s half-life is the amount of time it takes for half of a drug’s dose to leave your system.
How many mg of aripiprazole are in an extended-release injectable im suspension?
extended-release injectable IM suspension (aripiprazole lauroxil [Aristada]) 441mg/prefilled syringe (300 mg of aripiprazole) 662mg/prefilled syringe (450 mg of aripiprazole) 882mg/prefilled syringe (600 mg of aripiprazole)
How often can you give aripiprazole injection?
-Administer by deep IM gluteal (441 mg, 662 mg, or 882 mg) or deltoid (441 mg only) injection once a month or every 6 weeks as prescribed; do not administer IV or subcutaneously. -Administer by IM gluteal or deltoid (675 mg only) injection ONCE with oral aripiprazole; do not administer IV or subcutaneously.
What is a aripiprazole injection?
Aripiprazole injection comes as a solution (liquid) to be injected into a muscle by a healthcare provider.
How is aripiprazole dose adjusted when it is withdrawn?
-When coadministered drug is withdrawn, aripiprazole dose should be adjusted to the original level over 1 to 2 weeks. -Patients receiving a combination of strong, moderate, and weak inhibitors of CYP450 3A4 and CYP450 2D6 may need an initial dose reduction to one-quarter of the usual dose with adjustments to achieve a clinical response.