What is the normal range for anti-dsDNA?

Reference Range: <30.0 IU/mL Negative 30.0 – 75.0 IU/mL Borderline >75.0 IU/mL Positive Negative is considered normal.

What can cause a false positive anti-dsDNA?

The problem with anti-dsDNA ELISAs is that they often give false-positive results due to binding of immune complexes (with negatively charged moieties) to the pre-coat intermediates (10,11).

What does equivocal anti-dsDNA mean?

Interpretation: A NORMAL result is < 10 IU/mL (NEGATIVE). An EQUIVOCAL result is 10 – 15 IU/mL. A POSITIVE result is > 15 IU/mL The results obtained by this method should serve as an aid to diagnosis and should not be interpreted as diagnostic in itself.

Can you test positive for anti-dsDNA and not have lupus?

Anti-double-stranded DNA (dsDNA) Patients with this antibody who do not have SLE usually have a similar illness, such as rheumatoid arthritis. Sometimes the test is positive in otherwise well family members of lupus patients. About 80% of SLE patients with active, untreated disease have positive tests.

What does dsDNA test for?

The anti-dsDNA (anti-double stranded DNA) antibody test is a blood test that looks for antibodies to double stranded DNA. The anti-dsDNA antibody test is a very specific test for Systemic Lupus Erythematosus (SLE) because Anti-dsDNA antibodies aren’t found in any other autoimmune disorders.

What does an equivocal antibody test mean?

Equivocal: Your test results could not be interpreted as Positive or Negative. The most common reasons for equivocal results are presence of an immune response but unclear if against the infection being tested for (COVID-19 in this case) or similar infections (the common cold is a type of coronavirus).

What does a positive anti dsDNA test mean?

Anti-Double Stranded DNA (Anti-dsDNA) The anti-dsDNA antibody test is a very specific test for Systemic Lupus Erythematosus (SLE). That’s because Anti-dsDNA antibodies aren’t found in any other autoimmune disorders other than SLE. A strongly positive anti-dsDNA antibody test makes it very likely that a person has SLE.

What is an anti-dsDNA test for SLE?

Anti-Double Stranded DNA (Anti-dsDNA) The anti-dsDNA (anti-double stranded DNA) antibody test is a blood test that looks for antibodies to double stranded DNA. The anti-dsDNA antibody test is a very specific test for Systemic Lupus Erythematosus (SLE) because Anti-dsDNA antibodies aren’t found in any other autoimmune disorders.

What is the anti-double stranded DNA test?

How is the test used? The anti-double stranded DNA (anti-dsDNA) test is used to help diagnose lupus (systemic lupus erythematosus, SLE) in a person who has a positive result on a test for antinuclear antibody (ANA) and has clinical signs and symptoms that suggest lupus.

What is an anti-dsDNA antibody?

Anti-double stranded DNA antibody (anti-dsDNA) is one of a group of autoantibodies called antinuclear antibodies (ANA). Normally, antibodies protect against infection, but autoantibodies are produced when a person’s immune system fails to adequately distinguish between “self” and “non-self.”