What is ThinPrep TIS and HPV?

The ThinPrep Pap test is the only liquid-based Pap test FDA approved for use with all current FDA-approved HPV tests. * It is also FDA cleared for chlamydia, gonorrhea and trichomoniasis testing from the same vial. Screening women with Aptima HPV assays helps providers optimize care for each patient.

What does ThinPrep Tis PAP mean?

ThinPrep Pap test: A modified Pap test technique designed to reduce some of the technical problems inherent in the traditional type of Pap smear. It removes contaminants such as blood and mucus which frequently obscure cells in the traditional Pap smear.

What does HPV specimen reflexed for cytology testing mean?

The HPV test is also used after a cytology test result of atypical squamous cells of undetermined significance (ASC-US) among persons aged >25 years (known as reflex HPV testing). Positive cytology and HPV tests are markers of cervical precancerous lesions, which often do not cause symptoms until they become invasive.

What are low grade squamous cells?

An area of abnormal cells that forms on the surface of certain organs, such as the cervix, vagina, vulva, anus, and esophagus. Low-grade squamous intraepithelial lesions look slightly abnormal when looked at under a microscope.

Can you have LSIL and not have HPV?

Background: Although low-grade squamous intraepithelial lesions (LSIL) most often are the result of infection by human papillomaviruses (HPV), a small proportion of women with LSIL have negative HPV tests. However, at the next 6-month follow-up visit, 12%-32% of the women with HPV-negative LSIL had a positive HPV test.

Can ASCUS turn into LSIL?

Progression of ASCUS in LSIL is found in 9.6% (N-12), and regression from LSIL in ASCUS is 12.6% (N-14), which shows that a grade of regression of LSIL in ASCUS is bigger by 3%. Progression of ASCUS and LSIL into HSIL is not found in patients with low-risk HPV 6 and 11 infection.

How do you do a ThinPrep Pap smear?

Insert the brush into the cervix until only the bottom- most fibers are exposed. Slowly rotate 1/4 or 1/2 turn in one direction. DO NOT OVER-ROTATE. …the brush as quickly as possible in the PreservCyt Solution by rotating the device in the solution 10 times while pushing against the PreservCyt vial wall.

Is the ThinPrep cytologic test suitable for cervical cancer screening?

The ThinPrep cytologic test (TCT), HPV DNA detection, and E6/E7 mRNA testing are widely used to screen for cervical abnormalities. Purpose: This study aimed to find a suitable meth … An efficient method that combines the ThinPrep cytologic test with E6/E7 mRNA testing for cervical cancer screening Cancer Manag Res.

Can the ThinPrep ® Pap test be used for vaginal smears?

Vaginal Pap smears can also be performed but must be noted on the requisition. The ThinPrep ® Pap test addresses these limitations with liquid-based preparation, improving specimen adequacy and significantly increasing test sensitivity.

How many ml of preservcyt solution is required for the HPV DNA test?

Specimens in ThinPrep® Cytyc PreservCyt™ Solution: There must be at least 4 mL of PreservCyt ™ solution remaining for the HPV DNA test. Storage/Transport Temperature: Submit specimens according to Biological Substance, Category B, shipping guidelines. Always record if a cytobrush was used to perform the Pap test.

What is the CPT code for high risk HPV DNA?

HPV DNA, High Risk with Reflex to Genotypes 16,18 Pap results requiring physician interpretation will be performed at an additional charge (CPT code (s): 88141; HCPCS: G0124). If the Pap is Normal and HPV DNA, High Risk is Detected, HPV Genotypes 16,18 will be performed at an additional charge (CPT code (s) 87625).