What is zevtera?
Ceftobiprole (Zevtera/Mabelio) is a fifth-generation cephalosporin for the treatment of hospital-acquired pneumonia (excluding ventilator-associated pneumonia) and community-acquired pneumonia.
What is Ceftobiprole good for?
Ceftobiprole is approved for the treatment of community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP), excluding ventilator-associated pneumonia, in several European and non-European countries.
What antibiotic class & which generation drug is ceftobiprole?
Introduction: Ceftobiprole is a fifth-generation cephalosporin with a broad spectrum of antimicrobial activity, including also methicillin-resistant Staphylococcus aureus (MRSA).
Why is ceftaroline active against MRSA?
Similar to all other beta-lactam antibiotics, ceftaroline inhibits bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). Ceftaroline’s affinity for PBP2a and PBP2x results in its bactericidal activity against MRSA and Streptococcus pneumoniae, respectively.