How is Lutate therapy administered?

Lu-177-DOTA Octreotate (Lutate) is administered. Lutate is infused over 20-30 minutes under the supervision of the Nuclear Medicine Physician. At the completion of the Lutate infusion, the amino acid infusion continues for a further 2-4 hours (as detailed above).

How long are you radioactive after PRRT?

After PRRT, you will be slightly radioactive. So you might need to stay in hospital for 1 or 2 days to make sure the radioactivity drops to a safe level before you go home. In some hospitals, you may be able to go home later the same day if you are feeling well.

How effective is PRRT treatment?

A number of clinical studies have demonstrated PRRT’s efficacy, and the overall response rate (including complete response, partial response, minor response, and stable disease) is about 70% to 80% for the most commonly used radiopharmaceuticals: yttrium-90 (90Y)-DOTATOC (best suited for treating larger tumors) and …

Can PRRT cure cancer?

PRRT is a treatment option that is highly effective in controlling advanced, metastatic or inoperable, progressive neuroendocrine tumors. PRRT is rarely curative but has been shown to help relieve symptoms, shrink tumor lesions, and slow the progression of the disease5.

What is Lutate treatment?

Lutate (177Lu-DOTATATE) treatment is used to treat some neuroendocrine tumours (NETs). It is a type of targeted internal radiotherapy called peptide receptor radionuclide therapy (PRRT) . Lutate treatment: uses a radioactive substance – radionuclide, Lutetium–to177.

What can I expect after PRRT treatment?

Some feel few if any effects and others feel fatigued and nauseated, so it is advised that you carry some anti-nausea medication with you just in case. For all patients it is advised that you continue to drink 2 to 3 liters a day for several days following discharge and while traveling.

Is PRRT painful?

PRRT with Lu 177 is generally well tolerated. Common side-effects of Lu-177 therapy are nausea, vomiting, and abdominal pain. Other less common side-effects are bone, liver and kidney toxicity, and mild hair loss.

What are the side effects of PRRT?

What are possible side effects after PRRT treatment? Every patient is different and may experience side effects differently. Common side effects include generalized fatigue, weakness, nausea, mild increase in flushing, mild increase in diarrhea, and changes in your bloodwork results.

What is Lutate? Lutate (177Lu-DOTATATE) treatment is used to treat some neuroendocrine tumours (NETs). It is a type of targeted internal radiotherapy called peptide receptor radionuclide therapy (PRRT). Lutate treatment:

What is LUTATHERA used to treat?

Lutathera® Treatment for Neuroendocrine Tumors at Moffitt Cancer Center. Lutathera is a breakthrough, FDA-approved treatment for adults with certain types of neuroendocrine tumors, or NETs, in the pancreas or gastrointestinal tract.

How does Lutathera treat neuroendocrine tumors?

This type of treatment uses high doses of radiation to destroy cancer cells while limiting harm to surrounding healthy tissues. Lutathera – the first drug of its kind to be approved for the treatment of neuroendocrine tumors –contains a radioactive substance that seeks out cancer-positive cells and attacks them.

What Lutate services does NSW have?

NSW has two designated Lutate services. Both of these services participated in NSW Health’s evaluation of Lutate therapy 1 and treat patients according to the NSW Lutate therapy referral and protocol for neuroendocrine cancer patients 2.