What are the contraindication of fibrinolytic therapy?

Relative contraindications (not absolute) to fibrinolytic therapy include: Uncontrolled hypertension (BP > 180/110), either currently or in the past. Intracranial abnormality not listed as absolute contraindication (i.e. benign intracranial tumor) Ischemic stroke more than 3 months prior.

What are the contraindications of alteplase?

Due to an increased risk for bleeding, alteplase is contraindicated in patients being treated for acute myocardial infarction or pulmonary embolism with the following concomitant conditions: severe uncontrolled hypertension, aneurysm or arteriovenous malformation; known coagulopathy or bleeding diathesis; active …

When is streptokinase contraindicated?

Because thrombolytic therapy increases the risk of bleeding, Streptase, Streptokinase, is contraindicated in the following situations: active internal bleeding. recent (within 2 months) cerebrovascular accident, intracranial or intraspinal surgery (see WARNINGS) intracranial neoplasm.

Who Cannot receive thrombolytic?

Thrombolytic therapy cannot be recommended for persons excluded from the NINDS Study6 for one of the following reasons: (1) current use of oral anticoagulants or a prothrombin time greater than 15 seconds (International Normalized Ratio [INR] greater than 1.7); (2) use of heparin in the previous 48 hours and a …

Why are thrombolytics contraindicated in hypertension?

Thrombolytic therapy is contraindicated in patients with a systolic blood pressure greater than 185 mmHg or diastolic blood pressure greater than 110 mmHg. Elevated blood pressure can lead to a delay in thrombolytic therapy, which is associated with increased morbidity.

What are the absolute contraindications to fibrinolytic therapy in a CV event?

Absolute contraindications Presence of a cerebral vascular malformation or a primary or metastatic intracranial malignancy. Symptoms or signs suggestive of an aortic dissection. A bleeding diathesis or active bleeding, (menstruation is an exception)

What is an absolute contraindication?

Absolute contraindication means that event or substance could cause a life-threatening situation. A procedure or medicine that falls under this category must be avoided.

What are the contraindications for administration of thrombolytic therapy?

Relative Contraindications for Thrombolytic Treatment Prolonged (>10 minutes) cardiopulmonary resuscitation (CPR) or major surgery within three weeks. History of ischemic stroke.

Why is ultrasound contraindicated in patients with pacemakers?

Patients having pacemakers are also at risk due to the possibility that the sound waves might alter the implant’s performance. In these instances, the chest area must be avoided. As metal conducts heat, which could damage surrounding tissue, ultrasound is contraindicated in regions where metallic implants exist.

What are the contraindications for alteplase therapy for acute intermittent sinusitis (AIS)?

Absolute contraindications for alteplase therapy for AIS include the following: History or evidence of ICH. Clinical presentation suggestive of SAH. Known arteriovenous malformation. Systolic BP exceeding 185 mm Hg or diastolic BP exceeding 110 mm Hg despite repeated measurements and treatment.

What are the side effects of reteplase?

Reteplase side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Reteplase increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop.

Why is the chest area a contraindication for ultrasound?

In these instances, the chest area must be avoided. As metal conducts heat, which could damage surrounding tissue, ultrasound is contraindicated in regions where metallic implants exist. Ultrasound cannot be used in areas of the body containing malignant tissues.